GCMS Workshop on Determination of Ethylene Glycol (EG) & Diethylene Glycol (DEG)
in Medicinal Syrup

Propylene glycol, glycerol, and sorbitol are commonly used in medicinal syrup as excipients. Their presence helps to improve the solubility of the active ingredients and impacted the taste of the medication. However, these raw materials are easily contaminated with toxic ethylene glycol (EG) and diethylene glycol (DEG) which have caught the attention of WHO, hence leading to the issuance of a global alert in this issue. In this workshop, Shimadzu will examine the usage of the Shimadzu GCMS-QP2020 NX to identify and quantify EG and DEG in medicinal syrup. The analysis will be demonstrated using the Fast Automated Scan/SIM Type (FASST) mode, which enables consecutive operation of scan mode and selected ion monitoring (SIM) mode for accurate qualification and quantitation within a single injection.

Date : 26 September 2023